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Icariin inhibits the expression of IL-1β, IL-6 and TNF-α induced by OGD/R through the IRE1/XBP1s pathway in microglia

CONTEXT: Icariin (ICA), a flavonol glycoside extracted from Epimedium brevicornum Maxim (Berberidaceae), has been proven to inhibit inflammatory response in ischaemic rats in our laboratory's previous work. However, its underlying mechanism is still unclear. OBJECTIVE: This study investigates t...

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Detalles Bibliográficos
Autores principales: Mo, Zhen-Tao, Zheng, Jie, Liao, Yu-ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555556/
https://www.ncbi.nlm.nih.gov/pubmed/34711127
http://dx.doi.org/10.1080/13880209.2021.1991959