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A novel paclitaxel coated balloon with increased drug transfer for treatment of complex vascular lesions

BACKGROUND: Drug coated balloons (DCB) with paclitaxel (Ptx) dose of 2–3.5 μg/mm(2) balloon surface inhibit restenosis with different effectiveness and duration of success. A clinical dose finding study is not known for any of the currently marketed products. The aim of the present preclinical trial...

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Detalles Bibliográficos
Autores principales: Gemeinhardt, Ole, Schnorr, Beatrix, Speck, Ulrich, Scheller, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555778/
https://www.ncbi.nlm.nih.gov/pubmed/34714843
http://dx.doi.org/10.1371/journal.pone.0259106