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A data-driven approach for constructing mutation categories for mutational signature analysis
Mutational processes shape the genomes of cancer patients and their understanding has important applications in diagnosis and treatment. Current modeling of mutational processes by identifying their characteristic signatures views each base substitution in a limited context of a single flanking base...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555780/ https://www.ncbi.nlm.nih.gov/pubmed/34665813 http://dx.doi.org/10.1371/journal.pcbi.1009542 |