Decreasing mitochondrial RNA polymerase activity reverses biased inheritance of hypersuppressive mtDNA

Faithful inheritance of mitochondrial DNA (mtDNA) is crucial for cellular respiration/oxidative phosphorylation and mitochondrial membrane potential. However, how mtDNA is transmitted to progeny is not fully understood. We utilized hypersuppressive mtDNA, a class of respiratory deficient Saccharomyc...

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Detalles Bibliográficos
Autores principales: Corbi, Daniel, Amon, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555793/
https://www.ncbi.nlm.nih.gov/pubmed/34665800
http://dx.doi.org/10.1371/journal.pgen.1009808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555793/
https://www.ncbi.nlm.nih.gov/pubmed/34665800
http://dx.doi.org/10.1371/journal.pgen.1009808

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