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In vivo rate-determining steps of tau seed accumulation in Alzheimer’s disease
Both the replication of protein aggregates and their spreading throughout the brain are implicated in the progression of Alzheimer’s disease (AD). However, the rates of these processes are unknown and the identity of the rate-determining process in humans has therefore remained elusive. By bringing...
Autores principales: | Meisl, Georg, Hidari, Eric, Allinson, Kieren, Rittman, Timothy, DeVos, Sarah L., Sanchez, Justin S., Xu, Catherine K., Duff, Karen E., Johnson, Keith A., Rowe, James B., Hyman, Bradley T., Knowles, Tuomas P. J., Klenerman, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555892/ https://www.ncbi.nlm.nih.gov/pubmed/34714685 http://dx.doi.org/10.1126/sciadv.abh1448 |
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