ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low-complexity domain

OCT4 and SOX2 confer pluripotency by recruiting coactivators to activate stem cell–specific transcription. However, the composition of coactivator complexes and their roles in maintaining stem cell fidelity remain unclear. Here, we report the ATP-binding cassette subfamily F member 1 (ABCF1) as a co...

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Detalles Bibliográficos
Autores principales: Choi, Eun-Bee, Vodnala, Munender, Zerbato, Madeleine, Wang, Jianing, Ho, Jaclyn J., Inouye, Carla, Ding, Lai, Fong, Yick W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555894/
https://www.ncbi.nlm.nih.gov/pubmed/34714667
http://dx.doi.org/10.1126/sciadv.abk2775

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