Large Lipoma of the Mouth Floor

Lipomas are one of the most common benign connective tissue masses in the human body. They rarely cause issues and are typically removed for cosmetic reasons. They rarely appear in the oral cavity though they are common. Thus, only a few sublingual lipoma cases have been reported. We present a case of a male in his 60s who came to our clinic complaining of dysphagia and dysarthria caused by an oral swelling from a right sublingual simple lipoma. It was decided to be removed surgically under general anesthesia, with neuromonitoring of the right hypoglossal nerve. The patient tolerated the surgery without complications and fully recovered with complete resolution of his mass effect symptoms. This case demonstrated the importance of having a wide differential diagnosis of oral lesions, especially in a patient with a complicated medical history. Though it is not used often, the case also demonstrated the neuroprotective effect of intraoperative hypoglossal nerve monitoring during sublingual surgeries.