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Sequence features of retrotransposons allow for epigenetic variability

Transposable elements (TEs) are mobile genetic elements that make up a large fraction of mammalian genomes. While select TEs have been co-opted in host genomes to have function, the majority of these elements are epigenetically silenced by DNA methylation in somatic cells. However, some TEs in mice,...

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Detalles Bibliográficos
Autores principales: Costello, Kevin R, Leung, Amy, Trac, Candi, Lee, Michael, Basam, Mudaser, Pospisilik, J Andrew, Schones, Dustin E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555987/
https://www.ncbi.nlm.nih.gov/pubmed/34668484
http://dx.doi.org/10.7554/eLife.71104

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