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A pilot open-label study of aldose reductase inhibition with AT-001 (caficrestat) in patients hospitalized for COVID-19 infection: Results from a registry-based matched-control analysis
BACKGROUND AND AIMS: Cardiometabolic disease may confer increased risk of adverse outcomes in COVID-19 patients by activation of the aldose reductase pathway. We hypothesized that aldose reductase inhibition with AT-001 might reduce viral inflammation and risk of adverse outcomes in diabetic patient...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd on behalf of Diabetes India.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556062/ https://www.ncbi.nlm.nih.gov/pubmed/34752935 http://dx.doi.org/10.1016/j.dsx.2021.102328 |
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por Gaztanaga, Juan, Ramasamy, Ravichandran, Schmidt, Ann Marie, Fishman, Glenn, Shendelman, Shoshana, Thangavelu, Karthinathan, Perfetti, Riccardo, Katz, Stuart D.
Publicado 2021
Enlace del recurso
Publicado 2021
Enlace del recurso
Online
Artículo
Texto