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What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes

Clostridioides difficile R20291 is the most studied PCR-Ribotype 027 isolate. The two predominant lineages of this hypervirulent strain, however, exhibit substantive phenotypic differences and possess genomes that differ by a small number of nucleotide changes. It is important that the source of R20...

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Detalles Bibliográficos
Autores principales: Monteford, Jorge, Bilverstone, Terry W., Ingle, Patrick, Philip, Sheryl, Kuehne, Sarah A., Minton, Nigel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556159/
https://www.ncbi.nlm.nih.gov/pubmed/34343672
http://dx.doi.org/10.1016/j.anaerobe.2021.102422
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author Monteford, Jorge
Bilverstone, Terry W.
Ingle, Patrick
Philip, Sheryl
Kuehne, Sarah A.
Minton, Nigel P.
author_facet Monteford, Jorge
Bilverstone, Terry W.
Ingle, Patrick
Philip, Sheryl
Kuehne, Sarah A.
Minton, Nigel P.
author_sort Monteford, Jorge
collection PubMed
description Clostridioides difficile R20291 is the most studied PCR-Ribotype 027 isolate. The two predominant lineages of this hypervirulent strain, however, exhibit substantive phenotypic differences and possess genomes that differ by a small number of nucleotide changes. It is important that the source of R20291 is taken into account in research outcomes.
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spelling pubmed-85561592021-11-08 What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes Monteford, Jorge Bilverstone, Terry W. Ingle, Patrick Philip, Sheryl Kuehne, Sarah A. Minton, Nigel P. Anaerobe Short Communication Clostridioides difficile R20291 is the most studied PCR-Ribotype 027 isolate. The two predominant lineages of this hypervirulent strain, however, exhibit substantive phenotypic differences and possess genomes that differ by a small number of nucleotide changes. It is important that the source of R20291 is taken into account in research outcomes. Academic Press 2021-10 /pmc/articles/PMC8556159/ /pubmed/34343672 http://dx.doi.org/10.1016/j.anaerobe.2021.102422 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Short Communication
Monteford, Jorge
Bilverstone, Terry W.
Ingle, Patrick
Philip, Sheryl
Kuehne, Sarah A.
Minton, Nigel P.
What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes
title What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes
title_full What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes
title_fullStr What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes
title_full_unstemmed What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes
title_short What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes
title_sort what's a snp between friends: the lineage of clostridioides difficile r20291 can effect research outcomes
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556159/
https://www.ncbi.nlm.nih.gov/pubmed/34343672
http://dx.doi.org/10.1016/j.anaerobe.2021.102422
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