Pancreatic cancer pathology viewed in the light of evolution

One way to understand ductal adenocarcinoma of the pancreas (pancreatic cancer) is to view it as unimaginably large numbers of evolving living organisms interacting with their environment. This “evolutionary view” creates both expected and surprising perspectives in all stages of neoplastic progress...

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Autores principales: Noë, Michaël, Hong, Seung-Mo, Wood, Laura D., Thompson, Elizabeth D., Roberts, Nicholas J., Goggins, Michael G., Klein, Alison P., Eshleman, James R., Kern, Scott E., Hruban, Ralph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556193/
https://www.ncbi.nlm.nih.gov/pubmed/33555482
http://dx.doi.org/10.1007/s10555-020-09953-z
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author Noë, Michaël
Hong, Seung-Mo
Wood, Laura D.
Thompson, Elizabeth D.
Roberts, Nicholas J.
Goggins, Michael G.
Klein, Alison P.
Eshleman, James R.
Kern, Scott E.
Hruban, Ralph H.
author_facet Noë, Michaël
Hong, Seung-Mo
Wood, Laura D.
Thompson, Elizabeth D.
Roberts, Nicholas J.
Goggins, Michael G.
Klein, Alison P.
Eshleman, James R.
Kern, Scott E.
Hruban, Ralph H.
author_sort Noë, Michaël
collection PubMed
description One way to understand ductal adenocarcinoma of the pancreas (pancreatic cancer) is to view it as unimaginably large numbers of evolving living organisms interacting with their environment. This “evolutionary view” creates both expected and surprising perspectives in all stages of neoplastic progression. Advances in the field will require greater attention to this critical evolutionary prospective.
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spelling pubmed-85561932021-11-04 Pancreatic cancer pathology viewed in the light of evolution Noë, Michaël Hong, Seung-Mo Wood, Laura D. Thompson, Elizabeth D. Roberts, Nicholas J. Goggins, Michael G. Klein, Alison P. Eshleman, James R. Kern, Scott E. Hruban, Ralph H. Cancer Metastasis Rev Article One way to understand ductal adenocarcinoma of the pancreas (pancreatic cancer) is to view it as unimaginably large numbers of evolving living organisms interacting with their environment. This “evolutionary view” creates both expected and surprising perspectives in all stages of neoplastic progression. Advances in the field will require greater attention to this critical evolutionary prospective. Springer US 2021-02-08 2021 /pmc/articles/PMC8556193/ /pubmed/33555482 http://dx.doi.org/10.1007/s10555-020-09953-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Noë, Michaël
Hong, Seung-Mo
Wood, Laura D.
Thompson, Elizabeth D.
Roberts, Nicholas J.
Goggins, Michael G.
Klein, Alison P.
Eshleman, James R.
Kern, Scott E.
Hruban, Ralph H.
Pancreatic cancer pathology viewed in the light of evolution
title Pancreatic cancer pathology viewed in the light of evolution
title_full Pancreatic cancer pathology viewed in the light of evolution
title_fullStr Pancreatic cancer pathology viewed in the light of evolution
title_full_unstemmed Pancreatic cancer pathology viewed in the light of evolution
title_short Pancreatic cancer pathology viewed in the light of evolution
title_sort pancreatic cancer pathology viewed in the light of evolution
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556193/
https://www.ncbi.nlm.nih.gov/pubmed/33555482
http://dx.doi.org/10.1007/s10555-020-09953-z
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