Shaping modern human skull through epigenetic, transcriptional and post-transcriptional regulation of the RUNX2 master bone gene

RUNX2 encodes the master bone transcription factor driving skeletal development in vertebrates, and playing a specific role in craniofacial and skull morphogenesis. The anatomically modern human (AMH) features sequence changes in the RUNX2 locus compared with archaic hominins’ species. We aimed to u...

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Detalles Bibliográficos
Autores principales: Di Pietro, Lorena, Barba, Marta, Palacios, Daniela, Tiberio, Federica, Prampolini, Chiara, Baranzini, Mirko, Parolini, Ornella, Arcovito, Alessandro, Lattanzi, Wanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556228/
https://www.ncbi.nlm.nih.gov/pubmed/34716352
http://dx.doi.org/10.1038/s41598-021-00511-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556228/
https://www.ncbi.nlm.nih.gov/pubmed/34716352
http://dx.doi.org/10.1038/s41598-021-00511-3

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