Ionizing radiation downregulates estradiol synthesis via endoplasmic reticulum stress and inhibits the proliferation of estrogen receptor-positive breast cancer cells

Breast cancer is a major threat to women’s health and estrogen receptor-positive (ER(+)) breast cancer exhibits the highest incidence among these cancers. As the primary estrogen, estradiol strongly promotes cellular proliferation and radiotherapy, as a standard treatment, exerts an excellent therap...

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Detalles Bibliográficos
Autores principales: Yang, Pengfei, Feng, Xiu, Li, Jin, Zhang, Tianyi, Sheng, Chengyan, Zhang, Liying, Hua, Junrui, Wei, Wenjun, Ding, Nan, He, Jinpeng, Zhang, Yanan, Wang, Jufang, Zhou, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556230/
https://www.ncbi.nlm.nih.gov/pubmed/34716300
http://dx.doi.org/10.1038/s41419-021-04328-w

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