Hsp70-containing extracellular vesicles are capable of activating of adaptive immunity in models of mouse melanoma and colon carcinoma

The release of Hsp70 chaperone from tumor cells is found to trigger the full-scale anti-cancer immune response. Such release and the proper immune reaction can be induced by the delivery of recombinant Hsp70 to a tumor and we sought to explore how the endogenous Hsp70 can be transported to extracell...

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Detalles Bibliográficos
Autores principales: Komarova, Elena Y., Suezov, Roman V., Nikotina, Alina D., Aksenov, Nikolay D., Garaeva, Luiza A., Shtam, Tatiana A., Zhakhov, Alexander V., Martynova, Marina G., Bystrova, Olga A., Istomina, Maria S., Ischenko, Alexander M., Margulis, Boris A., Guzhova, Irina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556270/
https://www.ncbi.nlm.nih.gov/pubmed/34716378
http://dx.doi.org/10.1038/s41598-021-00734-4

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