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BET protein inhibition evidently enhances sensitivity to PI3K/mTOR dual inhibition in intrahepatic cholangiocarcinoma

Intrahepatic cholangiocarcinoma (ICC), the second most common primary liver cancer, is a fatal malignancy with a poor prognosis and only very limited therapeutic options. Although molecular targeted therapy is emerged as a promising treatment strategy, resistance to molecular-targeted therapy occurs...

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Detalles Bibliográficos
Autores principales:	Miao, Xiaolong, Liu, Chen, Jiang, Yuancong, Wang, Yao, Kong, Deqiang, Wu, Zelai, Wang, Xinyi, Tian, Rui, Yu, Xing, Zhu, Xuhang, Gong, Weihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556340/ https://www.ncbi.nlm.nih.gov/pubmed/34716294 http://dx.doi.org/10.1038/s41419-021-04305-3

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