High-throughput and high-efficiency sample preparation for single-cell proteomics using a nested nanowell chip

Global quantification of protein abundances in single cells could provide direct information on cellular phenotypes and complement transcriptomics measurements. However, single-cell proteomics is still immature and confronts many technical challenges. Herein we describe a nested nanoPOTS (N2) chip t...

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Detalles Bibliográficos
Autores principales: Woo, Jongmin, Williams, Sarah M., Markillie, Lye Meng, Feng, Song, Tsai, Chia-Feng, Aguilera-Vazquez, Victor, Sontag, Ryan L., Moore, Ronald J., Hu, Dehong, Mehta, Hardeep S., Cantlon-Bruce, Joshua, Liu, Tao, Adkins, Joshua N., Smith, Richard D., Clair, Geremy C., Pasa-Tolic, Ljiljana, Zhu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556371/
https://www.ncbi.nlm.nih.gov/pubmed/34716329
http://dx.doi.org/10.1038/s41467-021-26514-2

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