Assessment of neurodegeneration and neuronal loss in aged 5XFAD mice

Neuronal loss resulting from progressive neurodegeneration is a major pathological feature of Alzheimer’s disease (AD). Here, we present a protocol to detect neurodegeneration, neuronal apoptosis, and neuronal loss in 5XFAD mouse strain, which is a well-established model for interrogating the molecu...

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Detalles Bibliográficos
Autores principales: Zhang, Liansheng, Li, Jie, Lin, Anning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556527/
https://www.ncbi.nlm.nih.gov/pubmed/34755118
http://dx.doi.org/10.1016/j.xpro.2021.100915

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