Apolipoprotein E-Containing Lipoproteins and LRP1 Protect From NMDA-Induced Excitotoxicity Associated With Reducing α2-Macroglobulin in Müller Glia

PURPOSE: Optic nerve damage leads to impairment of visual functions. We previously demonstrated that apolipoprotein E-containing lipoproteins (E-LPs) protect retinal ganglion cells (RGCs) from degeneration in a glaucoma model of glutamate/aspartate transporter-deficient mice. This study aimed to det...

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Detalles Bibliográficos
Autores principales: Hayashi, Hideki, Mori, Misuzu, Harashima, Mina, Hashizume, Tatsuya, Furiya, Miho, Mukaigaito, Chihaya, Takemura, Emi, Yamada, Mariko, Mise, Kanako, Yuan, Bo, Takagi, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556555/
https://www.ncbi.nlm.nih.gov/pubmed/34698771
http://dx.doi.org/10.1167/iovs.62.13.23

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