COVID-19, Acute Myocardial Injury, and Infarction

Severe acute respiratory syndrome coronavirus-2 can affect the cardiovascular system yielding a wide range of complications, including acute myocardial injury. The myocardium can be damaged by direct viral invasion or indirect mechanisms, sustained by systemic inflammation, immune-mediated response,...

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Autores principales: Del Prete, Armando, Conway, Francesca, Della Rocca, Domenico G., Biondi-Zoccai, Giuseppe, De Felice, Francesco, Musto, Carmine, Picichè, Marco, Martuscelli, Eugenio, Natale, Andrea, Versaci, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556597/
https://www.ncbi.nlm.nih.gov/pubmed/35221083
http://dx.doi.org/10.1016/j.ccep.2021.10.004
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author Del Prete, Armando
Conway, Francesca
Della Rocca, Domenico G.
Biondi-Zoccai, Giuseppe
De Felice, Francesco
Musto, Carmine
Picichè, Marco
Martuscelli, Eugenio
Natale, Andrea
Versaci, Francesco
author_facet Del Prete, Armando
Conway, Francesca
Della Rocca, Domenico G.
Biondi-Zoccai, Giuseppe
De Felice, Francesco
Musto, Carmine
Picichè, Marco
Martuscelli, Eugenio
Natale, Andrea
Versaci, Francesco
author_sort Del Prete, Armando
collection PubMed
description Severe acute respiratory syndrome coronavirus-2 can affect the cardiovascular system yielding a wide range of complications, including acute myocardial injury. The myocardium can be damaged by direct viral invasion or indirect mechanisms, sustained by systemic inflammation, immune-mediated response, and dysregulation of the renin-angiotensin system. Myocardial injury affects about one-quarter of patients with COVID-19, can manifest even in the absence of previous cardiovascular disease, and is associated to higher mortality rates and long-term sequelae. This review describes the pathophysiological mechanisms of myocardial injury and infarction and discusses the main clinical outcomes and diagnostic challenges associated with myocardial damage during COVID-19.
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spelling pubmed-85565972021-11-01 COVID-19, Acute Myocardial Injury, and Infarction Del Prete, Armando Conway, Francesca Della Rocca, Domenico G. Biondi-Zoccai, Giuseppe De Felice, Francesco Musto, Carmine Picichè, Marco Martuscelli, Eugenio Natale, Andrea Versaci, Francesco Card Electrophysiol Clin Article Severe acute respiratory syndrome coronavirus-2 can affect the cardiovascular system yielding a wide range of complications, including acute myocardial injury. The myocardium can be damaged by direct viral invasion or indirect mechanisms, sustained by systemic inflammation, immune-mediated response, and dysregulation of the renin-angiotensin system. Myocardial injury affects about one-quarter of patients with COVID-19, can manifest even in the absence of previous cardiovascular disease, and is associated to higher mortality rates and long-term sequelae. This review describes the pathophysiological mechanisms of myocardial injury and infarction and discusses the main clinical outcomes and diagnostic challenges associated with myocardial damage during COVID-19. Elsevier Inc. 2022-03 2021-10-30 /pmc/articles/PMC8556597/ /pubmed/35221083 http://dx.doi.org/10.1016/j.ccep.2021.10.004 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Del Prete, Armando
Conway, Francesca
Della Rocca, Domenico G.
Biondi-Zoccai, Giuseppe
De Felice, Francesco
Musto, Carmine
Picichè, Marco
Martuscelli, Eugenio
Natale, Andrea
Versaci, Francesco
COVID-19, Acute Myocardial Injury, and Infarction
title COVID-19, Acute Myocardial Injury, and Infarction
title_full COVID-19, Acute Myocardial Injury, and Infarction
title_fullStr COVID-19, Acute Myocardial Injury, and Infarction
title_full_unstemmed COVID-19, Acute Myocardial Injury, and Infarction
title_short COVID-19, Acute Myocardial Injury, and Infarction
title_sort covid-19, acute myocardial injury, and infarction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556597/
https://www.ncbi.nlm.nih.gov/pubmed/35221083
http://dx.doi.org/10.1016/j.ccep.2021.10.004
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