Microglia and macrophage exhibit attenuated inflammatory response and ferroptosis resistance after RSL3 stimulation via increasing Nrf2 expression

BACKGROUND: Many neurological diseases involve neuroinflammation, during which overproduction of cytokines by immune cells, especially microglia, can aggregate neuronal death. Ferroptosis is a recently discovered cell metabolism-related form of cell death and RSL3 is a well-known inducer of cell fer...

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Detalles Bibliográficos
Autores principales: Cui, Yu, Zhang, Zhaolong, Zhou, Xin, Zhao, Zhiyuan, Zhao, Rui, Xu, Xiangyu, Kong, Xiangyi, Ren, Jinyang, Yao, Xujin, Wen, Qian, Guo, Feifei, Gao, Shengli, Sun, Jiangdong, Wan, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557003/
https://www.ncbi.nlm.nih.gov/pubmed/34717678
http://dx.doi.org/10.1186/s12974-021-02231-x

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