p53 is functionally inhibited in clear cell renal cell carcinoma (ccRCC): a mechanistic and correlative investigation into genetic and molecular characteristics

PURPOSE: Although p53 is rarely mutated in ccRCC, its overexpression has been linked to poor prognosis. The current study sought to elucidate the unique role of p53 in ccRCC with genomic, proteomic, and functional analyses. MATERIALS AND METHODS: Data from the Cancer Genome Atlas (TCGA) were evaluat...

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Detalles Bibliográficos
Autores principales: Diesing, Karoline, Ribback, Silvia, Winter, Stefan, Gellert, Manuela, Oster, Antonia M., Stühler, Viktoria, Gläser, Eva, Adler, Frank, Hartwig, Christoph, Scharpf, Markus, Bedke, Jens, Burchardt, Martin, Schwab, Matthias, Lillig, Christopher H., Kroeger, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article – Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557161/
https://www.ncbi.nlm.nih.gov/pubmed/34499221
http://dx.doi.org/10.1007/s00432-021-03786-1

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