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The Key Regulator of Necroptosis, RIP1 Kinase, Contributes to the Formation of Astrogliosis and Glial Scar in Ischemic Stroke

Necroptosis initiation relies on the receptor-interacting protein 1 kinase (RIP1K). We recently reported that genetic and pharmacological inhibition of RIP1K produces protection against ischemic stroke-induced astrocytic injury. However, the role of RIP1K in ischemic stroke-induced formation of astr...

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Detalles Bibliográficos
Autores principales: Zhu, Yong-Ming, Lin, Liang, Wei, Chao, Guo, Yi, Qin, Yuan, Li, Zhong-Sheng, Kent, Thomas A., McCoy, Claire E., Wang, Zhan-Xiang, Ni, Yong, Zhou, Xian-Yong, Zhang, Hui-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557200/
https://www.ncbi.nlm.nih.gov/pubmed/33629276
http://dx.doi.org/10.1007/s12975-021-00888-3