Cargando…

Nrf2/Keap1/ARE signaling: Towards specific regulation

The Nrf2 transcription factor governs the expression of hundreds genes involved in cell defense against oxidative stress, the hallmark of numerous diseases such as neurodegenerative, cardiovascular, some viral pathologies, diabetes and others. The main route for Nrf2 activity regulation is via inter...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ulasov, Alexey V., Rosenkranz, Andrey A., Georgiev, Georgii P., Sobolev, Alexander S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557391/ https://www.ncbi.nlm.nih.gov/pubmed/34732330 http://dx.doi.org/10.1016/j.lfs.2021.120111

Ejemplares similares

An Approach to Evaluate the Effective Cytoplasmic Concentration of Bioactive Agents Interacting with a Selected Intracellular Target Protein
por: Khramtsov, Yuri V., et al.
Publicado: (2023)

Mouse Syngeneic Melanoma Model with Human Epidermal Growth Factor Receptor Expression
por: Slastnikova, Tatiana A., et al.
Publicado: (2022)

Targeted Delivery of (111)In Into the Nuclei of EGFR Overexpressing Cells via Modular Nanotransporters With Anti-EGFR Affibody
por: Karyagina, Tatiana S., et al.
Publicado: (2020)

Keap1/Nrf2 Signaling Pathway
por: Sykiotis, Gerasimos P.
Publicado: (2021)

Molecular and Chemical Regulation of the Keap1-Nrf2 Signaling Pathway
por: Keum, Young-Sam, et al.
Publicado: (2014)

The KEAP1/NRF2 Signaling Pathway in Keratinization
por: Ishitsuka, Yosuke, et al.
Publicado: (2020)

Modulation of NRF2/KEAP1 Signaling in Preeclampsia
por: Tossetta, Giovanni, et al.
Publicado: (2023)

Epigenetic Regulation of NRF2/KEAP1 by Phytochemicals
por: Bhattacharjee, Shamee, et al.
Publicado: (2020)

The Keap1/Nrf2 Signaling Pathway in the Thyroid—2020 Update
por: Thanas, Christina, et al.
Publicado: (2020)

WDR23 regulates NRF2 independently of KEAP1
por: Lo, Jacqueline Y., et al.
Publicado: (2017)

Antitumor Activity of Auger Electron Emitter (111)In Delivered by Modular Nanotransporter for Treatment of Bladder Cancer With EGFR Overexpression
por: Rosenkranz, Andrey A., et al.
Publicado: (2018)

Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway
por: Hassanein, Emad H. M., et al.
Publicado: (2020)

Molecular Basis of the KEAP1-NRF2 Signaling Pathway
por: Suzuki, Takafumi, et al.
Publicado: (2023)

Insights into the Regulation of GFR by the Keap1-Nrf2 Pathway
por: Kidokoro, Kengo, et al.
Publicado: (2023)

The spatiotemporal regulation of the Keap1–Nrf2 pathway and its importance in cellular bioenergetics
por: Dinkova-Kostova, Albena T., et al.
Publicado: (2015)

The emerging role of the Nrf2–Keap1 signaling pathway in cancer
por: Jaramillo, Melba C., et al.
Publicado: (2013)

The Role of NRF2/KEAP1 Signaling Pathway in Cancer Metabolism
por: Song, Moon-Young, et al.
Publicado: (2021)

Signal amplification in the KEAP1-NRF2-ARE antioxidant response pathway
por: Liu, Shengnan, et al.
Publicado: (2022)

Cell-specific and roasting-dependent regulation of the Keap1/Nrf2 pathway by coffee extracts
por: Priftis, Alexandros, et al.
Publicado: (2018)

The KEAP1–NRF2 System in Cancer
por: Taguchi, Keiko, et al.
Publicado: (2017)

Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway
por: Copple, Ian M., et al.
Publicado: (2010)

Nomilin targets the Keap1‐Nrf2 signalling and ameliorates the development of osteoarthritis
por: Xue, Xing‐He, et al.
Publicado: (2020)

Mathematical modeling reveals quantitative properties of KEAP1-NRF2 signaling
por: Liu, Shengnan, et al.
Publicado: (2021)

The role of the Nrf2/Keap1 signaling cascade in mechanobiology and bone health
por: Priddy, Carlie, et al.
Publicado: (2021)

The potential roles of Nrf2/Keap1 signaling in anticancer drug interactions
por: Wang, Jingya, et al.
Publicado: (2021)

Keap1/Nrf2 Signaling: A New Player in Thyroid Pathophysiology and Thyroid Cancer
por: Renaud, Cedric O., et al.
Publicado: (2019)

Catalpol Exerts an Anti-Epilepticus Effect, Possibly by Regulating the Nrf2-Keap1-ARE Signaling Pathway
por: Gao, Jing, et al.
Publicado: (2018)

Zhibaidihuang Decoction Ameliorates Cell Oxidative Stress by Regulating the Keap1-Nrf2-ARE Signalling Pathway
por: Wu, Pingping, et al.
Publicado: (2020)

Pharmacological Protection against Ischemia-Reperfusion Injury by Regulating the Nrf2-Keap1-ARE Signaling Pathway
por: Ucar, Bercis Imge, et al.
Publicado: (2021)

Role and Mechanism of Keap1/Nrf2 Signaling Pathway in the Regulation of Autophagy in Alleviating Pulmonary Fibrosis
por: Dong, Zhaoxing, et al.
Publicado: (2022)

KEAP1 and done? Targeting the NRF2 pathway with sulforaphane
por: Dinkova-Kostova, Albena T., et al.
Publicado: (2017)

Structural basis of Keap1 interactions with Nrf2
por: Canning, Peter, et al.
Publicado: (2015)

The KEAP1-NRF2 System and Esophageal Cancer
por: Hirose, Wataru, et al.
Publicado: (2022)

Evidence of Nrf2/Keap1 Signaling Regulation by Mitochodria-Generated Reactive Oxygen Species in RGK1 Cells
por: Indo, Hiroko P., et al.
Publicado: (2023)

Mechanism of oxidative stress and Keap-1/Nrf2 signaling pathway in bronchopulmonary dysplasia
por: Ma, Di, et al.
Publicado: (2020)

Modulation of Keap1/Nrf2/ARE Signaling Pathway by Curcuma- and Garlic-Derived Hybrids
por: Serafini, Melania Maria, et al.
Publicado: (2020)

Epigenetic Therapeutics Targeting NRF2/KEAP1 Signaling in Cancer Oxidative Stress
por: Zhang, Shunhao, et al.
Publicado: (2022)

LBP reduces theinflammatory injuryof kidney in septic rat and regulates the Keap1-Nrf2∕ARE signaling pathway
por: Huang, Yayi, et al.
Publicado: (2019)

Regulation of Keap-1/Nrf2 Signaling Pathway Is Activated by Oxidative Stress in Patients with Premature Rupture of Membranes
por: Zhang, Wenfeng, et al.
Publicado: (2020)

The chromatin-remodeling enzyme Smarca5 regulates erythrocyte aggregation via Keap1-Nrf2 signaling
por: Ding, Yanyan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_plfgp5n0hgujmh4cgn2f98oal6