Evolution of Renal-Disease Factor APOL1 Results in Cis and Trans Orientations at the Endoplasmic Reticulum That Both Show Cytotoxic Effects

The recent and exclusively in humans and a few other higher primates expressed APOL1 (apolipoprotein L1) gene is linked to African human trypanosomiasis (also known as African sleeping sickness) as well as to different forms of kidney diseases. Whereas APOL1’s role as a trypanolytic factor is well e...

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Detalles Bibliográficos
Autores principales: Müller, Daria, Schmitz, Jürgen, Fischer, Katharina, Granado, Daniel, Groh, Ann-Christin, Krausel, Vanessa, Lüttgenau, Simona Mareike, Amelung, Till Maximilian, Pavenstädt, Hermann, Weide, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557400/
https://www.ncbi.nlm.nih.gov/pubmed/34323996
http://dx.doi.org/10.1093/molbev/msab220

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