Reversal of pulmonary arterial hypertension and neointimal formation by kinin B1 receptor blockade

BACKGROUND: This study examined whether BI113823, a novel selective kinin B1 receptor antagonist can reverse established pulmonary arterial hypertension (PAH), prevent right heart failure and death, which is critical for clinical translation. METHODS: Left pneumonectomized male Wistar rats were inje...

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Detalles Bibliográficos
Autores principales: Rampa, Dileep Reddy, Murugesan, Priya, Chao, Honglu, Feng, Huiying, Dai, Wenxin, Lee, Dongwon, Pekcec, Anton, Doods, Henri, Wu, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557528/
https://www.ncbi.nlm.nih.gov/pubmed/34717626
http://dx.doi.org/10.1186/s12931-021-01875-w

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