Nanomaterial- and shape-dependency of TLR2 and TLR4 mediated signaling following pulmonary exposure to carbonaceous nanomaterials in mice

BACKGROUND: Pulmonary exposure to high doses of engineered carbonaceous nanomaterials (NMs) is known to trigger inflammation in the lungs paralleled by an acute phase response. Toll-like receptors (TLRs), particularly TLR2 and TLR4, have recently been discussed as potential NM-sensors, initiating in...

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Detalles Bibliográficos
Autores principales: Danielsen, Pernille Høgh, Bendtsen, Katja Maria, Knudsen, Kristina Bram, Poulsen, Sarah Søs, Stoeger, Tobias, Vogel, Ulla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557558/
https://www.ncbi.nlm.nih.gov/pubmed/34717665
http://dx.doi.org/10.1186/s12989-021-00432-z

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