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Diverse antiviral IgG effector activities are predicted by unique biophysical antibody features
BACKGROUND: The critical role of antibody Fc-mediated effector functions in immune defense has been widely reported in various viral infections. These effector functions confer cellular responses through engagement with innate immune cells. The precise mechanism(s) by which immunoglobulin G (IgG) Fc...
Autores principales: | Cheng, Hao D., Dowell, Karen G., Bailey-Kellogg, Chris, Goods, Brittany A., Love, J. Christopher, Ferrari, Guido, Alter, Galit, Gach, Johannes, Forthal, Donald N., Lewis, George K., Greene, Kelli, Gao, Hongmei, Montefiori, David C., Ackerman, Margaret E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557579/ https://www.ncbi.nlm.nih.gov/pubmed/34717659 http://dx.doi.org/10.1186/s12977-021-00579-9 |
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