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Serum-derived exosomes promote CD8+ T cells to overexpress PD-1, affecting the prognosis of hypopharyngeal carcinoma

BACKGROUND: Hypopharyngeal cancer (HPC) is associated with a poor prognosis and a high recurrence rate. Immune escape is one of the reasons for the poor prognosis of malignant tumors. Programmed cell death ligand 1 (PD-L1) and programmed cell death-1 (PD-1) have been shown to play important roles in...

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Detalles Bibliográficos
Autores principales:	Gao, Qian, Liu, Hui-Ting, Xu, Yu-Qin, Zhang, Lin, Liu, Yuan-Ru, Ren, Qianqian, Sheng, Ju-ping, Zhang, Zhen-Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557583/ https://www.ncbi.nlm.nih.gov/pubmed/34717645 http://dx.doi.org/10.1186/s12935-021-02294-z

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