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Activation of adult mammalian retinal stem cells in vivo via antagonism of BMP and sFRP2

BACKGROUND: The adult mammalian retina does not have the capacity to regenerate cells lost due to damage or disease. Therefore, retinal injuries and blinding diseases result in irreversible vision loss. However, retinal stem cells (RSCs), which participate in retinogenesis during development, persis...

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Detalles Bibliográficos
Autores principales:	Grisé, Kenneth N., Coles, Brenda L. K., Bautista, Nelson X., van der Kooy, Derek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557620/ https://www.ncbi.nlm.nih.gov/pubmed/34717744 http://dx.doi.org/10.1186/s13287-021-02630-0

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