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Targeted Hybridization Capture of SARS-CoV-2 and Metagenomics Enables Genetic Variant Discovery and Nasal Microbiome Insights

The emergence of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genetic variants that may alter viral fitness highlights the urgency of widespread next-generation sequencing (NGS) surveillance. To profile genetic variants of the entire SARS-CoV-2 genome, we developed and clinical...

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Detalles Bibliográficos
Autores principales: Nagy-Szakal, Dorottya, Couto-Rodriguez, Mara, Wells, Heather L., Barrows, Joseph E., Debieu, Marilyne, Butcher, Kristin, Chen, Siyuan, Berki, Agnes, Hager, Courteny, Boorstein, Robert J., Taylor, Mariah K., Jonsson, Colleen B., Mason, Christopher E., O’Hara, Niamh B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557865/
https://www.ncbi.nlm.nih.gov/pubmed/34468193
http://dx.doi.org/10.1128/Spectrum.00197-21