Cargando…

Novel Antifungal Activity of Q-Griffithsin, a Broad-Spectrum Antiviral Lectin

There is a rising global incidence of Candida strains with high levels of resistance to fluconazole and other antifungal drugs, hence the need for novel antifungal treatment strategies. Here, we describe the first evidence of antifungal activity of Q-Griffithsin (Q-GRFT), a recombinant oxidation-res...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nabeta, Henry W., Kouokam, Joseph C., Lasnik, Amanda B., Fuqua, Joshua L., Palmer, Kenneth E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557872/ https://www.ncbi.nlm.nih.gov/pubmed/34494857 http://dx.doi.org/10.1128/Spectrum.00957-21

Ejemplares similares

Antiviral lectin Q-Griffithsin suppresses fungal infection in murine models of vaginal candidiasis
por: Nabeta, Henry W., et al.
Publicado: (2022)

Bulk production of the antiviral lectin griffithsin
por: Fuqua, Joshua L., et al.
Publicado: (2015)

Pharmacokinetics of the Antiviral Lectin Griffithsin Administered by Different Routes Indicates Multiple Potential Uses
por: Barton, Christopher, et al.
Publicado: (2016)

Studies in a Murine Model Confirm the Safety of Griffithsin and Advocate Its Further Development as a Microbicide Targeting HIV-1 and Other Enveloped Viruses
por: Kouokam, Joseph Calvin, et al.
Publicado: (2016)

Griffithsin: An Antiviral Lectin with Outstanding Therapeutic Potential
por: Lusvarghi, Sabrina, et al.
Publicado: (2016)

Preformulation Characterization of Griffithsin, a Biopharmaceutical Candidate for HIV Prevention
por: Kramzer, Lindsay F., et al.
Publicado: (2021)

Griffithsin, a Highly Potent Broad-Spectrum Antiviral Lectin from Red Algae: From Discovery to Clinical Application
por: Lee, Choongho
Publicado: (2019)

Improving the large scale purification of the HIV microbicide, griffithsin
por: Fuqua, Joshua L, et al.
Publicado: (2015)

In vitro Study on Synergistic Interactions Between Free and Encapsulated Q-Griffithsin and Antiretrovirals Against HIV-1 Infection
por: Minooei, Farnaz, et al.
Publicado: (2021)

Characterization of the hypersensitive response‐like cell death phenomenon induced by targeting antiviral lectin griffithsin to the secretory pathway
por: Kim, Bo Min, et al.
Publicado: (2018)

Technoeconomic Modeling of Plant-Based Griffithsin Manufacturing
por: Alam, Aatif, et al.
Publicado: (2018)

Development and validation of a product acceptability questionnaire for intranasal Q-Griffithsin COVID-19 prophylaxis (SPRAY PAL)
por: Cash, Elizabeth, et al.
Publicado: (2023)

In Preparation for Outdoor Pharming: Griffithsin Can Be Expressed in Nicotiana excelsiana and Retains Activity After Storage as Silage
por: Eapen, Paul, et al.
Publicado: (2020)

Integrated autolysis, DNA hydrolysis and precipitation enables an improved bioprocess for Q-Griffithsin, a broad-spectrum antiviral and clinical-stage anti-COVID-19 candidate
por: Decker, John S., et al.
Publicado: (2022)

Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus
por: Moulaei, Tinoush, et al.
Publicado: (2015)

Low-Cost, Large-Scale Production of the Anti-viral Lectin Griffithsin
por: Decker, John S., et al.
Publicado: (2020)

An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo
por: Zhao, Yajing, et al.
Publicado: (2022)

Investigation of Griffithsin's Interactions with Human Cells Confirms Its Outstanding Safety and Efficacy Profile as a Microbicide Candidate
por: Kouokam, Joseph Calvin, et al.
Publicado: (2011)

Domain-Swapped Structure of the Potent Antiviral Protein Griffithsin and Its Mode of Carbohydrate Binding
por: Ziółkowska, Natasza E., et al.
Publicado: (2006)

Crystallographic studies of the complexes of antiviral protein griffithsin with glucose and N-acetylglucosamine
por: Ziółkowska, Natasza E., et al.
Publicado: (2007)

In vitro antiviral activity of Griffithsin against porcine epidemic diarrhea virus
por: Li, Lan, et al.
Publicado: (2019)

Synergistic anti-HIV-1 activity of griffithsin with tenofovir, maraviroc and enfuvirtide
por: Férir, Geoffrey, et al.
Publicado: (2011)

Grifonin-1: A Small HIV-1 Entry Inhibitor Derived from the Algal Lectin, Griffithsin
por: Micewicz, Ewa D., et al.
Publicado: (2010)

Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin
por: Millet, Jean K., et al.
Publicado: (2016)

Broad-Spectrum Antiviral Therapeutics
por: Rider, Todd H., et al.
Publicado: (2011)

Broad-spectrum antiviral agents
por: Zhu, Jun-Da, et al.
Publicado: (2015)

Broad-Spectrum Antivirals and Antiviral Drug Combinations
por: Oksenych, Valentyn, et al.
Publicado: (2022)

Broad-Spectrum Antivirals and Antiviral Combinations: An Editorial Update
por: Kainov, Denis, et al.
Publicado: (2022)

Modified cyclodextrins as broad-spectrum antivirals
por: Jones, Samuel T., et al.
Publicado: (2020)

Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge
por: Lo, Michael K, et al.
Publicado: (2020)

Plant-Derived Lectins as Potential Cancer Therapeutics and Diagnostic Tools
por: Mazalovska, Milena, et al.
Publicado: (2020)

Broad-spectrum antifungal activities and mechanism of drimane sesquiterpenoids
por: Edouarzin, Edruce, et al.
Publicado: (2020)

Griffithsin with A Broad-Spectrum Antiviral Activity by Binding Glycans in Viral Glycoprotein Exhibits Strong Synergistic Effect in Combination with A Pan-Coronavirus Fusion Inhibitor Targeting SARS-CoV-2 Spike S2 Subunit
por: Cai, Yanxing, et al.
Publicado: (2020)

Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture
por: Shrivastava-Ranjan, Punya, et al.
Publicado: (2020)

Lectins as Promising Therapeutics for the Prevention and Treatment of HIV and Other Potential Coinfections
por: Mazalovska, Milena, et al.
Publicado: (2018)

Broad-spectrum antivirals against viral fusion
por: Vigant, Frederic, et al.
Publicado: (2015)

Arbidol as a broad-spectrum antiviral: An update
por: Blaising, Julie, et al.
Publicado: (2014)

Broad-Spectrum Antiviral Strategies and Nucleoside Analogues
por: Geraghty, Robert J., et al.
Publicado: (2021)

dsRNA as broad-spectrum antiviral therapeutics
por: Xu, Congfei
Publicado: (2022)

Novel activities of safe-in-human broad-spectrum antiviral agents
por: Ianevski, Aleksandr, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_gjdgvlnhmo5ghkc8f6e6gfeb34