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Reproducibility of the Ribosomal RNA Synthesis Ratio in Sputum and Association with Markers of Mycobacterium tuberculosis Burden

There is a critical need for improved pharmacodynamic markers for use in human tuberculosis (TB) drug trials. Pharmacodynamic monitoring in TB has conventionally used culture or molecular methods to enumerate the burden of Mycobacterium tuberculosis organisms in sputum. A recently proposed assay cal...

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Detalles Bibliográficos
Autores principales:	Musisi, Emmanuel, Dide-Agossou, Christian, Al Mubarak, Reem, Rossmassler, Karen, Ssesolo, Abdul Wahab, Kaswabuli, Sylvia, Byanyima, Patrick, Sanyu, Ingvar, Zawedde, Josephine, Worodria, William, Voskuil, Martin I., Savic, Rada M., Nahid, Payam, Davis, J. Lucian, Huang, Laurence, Moore, Camille M., Walter, Nicholas D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557932/ https://www.ncbi.nlm.nih.gov/pubmed/34494858 http://dx.doi.org/10.1128/Spectrum.00481-21

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