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Sex-dependent effects of amyloid precursor-like protein 2 in the SOD1-G37R transgenic mouse model of MND

Motor neurone disease (MND) is a neurodegenerative disorder characterised by progressive destruction of motor neurons, muscle paralysis and death. The amyloid precursor protein (APP) is highly expressed in the central nervous system and has been shown to modulate disease outcomes in MND. APP is part...

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Detalles Bibliográficos
Autores principales:	Truong, Phan H., Crouch, Peter J., Hilton, James B. W., McLean, Catriona A., Cappai, Roberto, Ciccotosto, Giuseppe D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558206/ https://www.ncbi.nlm.nih.gov/pubmed/34476545 http://dx.doi.org/10.1007/s00018-021-03924-5

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