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Application of Machine Learning and Weighted Gene Co-expression Network Algorithm to Explore the Hub Genes in the Aging Brain

Aging is a major risk factor contributing to neurodegeneration and dementia. However, it remains unclarified how aging promotes these diseases. Here, we use machine learning and weighted gene co-expression network (WGCNA) to explore the relationship between aging and gene expression in the human fro...

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Detalles Bibliográficos
Autores principales: Chai, Keping, Liang, Jiawei, Zhang, Xiaolin, Cao, Panlong, Chen, Shufang, Gu, Huaqian, Ye, Weiping, Liu, Rong, Hu, Wenjun, Peng, Caixia, Liu, Gang Logan, Shen, Daojiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558222/
https://www.ncbi.nlm.nih.gov/pubmed/34733151
http://dx.doi.org/10.3389/fnagi.2021.707165