Genome-wide mRNA profiling identifies X-box-binding protein 1 (XBP1) as an IRE1 and PUMA repressor

Accumulation of misfolded proteins in ER activates the unfolded protein response (UPR), a multifunctional signaling pathway that is important for cell survival. The UPR is regulated by three ER transmembrane sensors, one of which is inositol-requiring protein 1 (IRE1). IRE1 activates a transcription...

Descripción completa

Detalles Bibliográficos
Autores principales: Gebert, Magdalena, Sobolewska, Aleksandra, Bartoszewska, Sylwia, Cabaj, Aleksandra, Crossman, David K., Króliczewski, Jarosław, Madanecki, Piotr, Dąbrowski, Michał, Collawn, James F., Bartoszewski, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558229/
https://www.ncbi.nlm.nih.gov/pubmed/34636989
http://dx.doi.org/10.1007/s00018-021-03952-1

Ejemplares similares

Ejemplares similares