Cargando…

Synaptic Release Potentiation at Aging Auditory Ribbon Synapses

Age-related hidden hearing loss is often described as a cochlear synaptopathy that results from a progressive degeneration of the inner hair cell (IHC) ribbon synapses. The functional changes occurring at these synapses during aging are not fully understood. Here, we characterized this aging process...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peineau, Thibault, Belleudy, Séverin, Pietropaolo, Susanna, Bouleau, Yohan, Dulon, Didier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558230/ https://www.ncbi.nlm.nih.gov/pubmed/34733152 http://dx.doi.org/10.3389/fnagi.2021.756449

Ejemplares similares

Hyperacusis in the Adult Fmr1-KO Mouse Model of Fragile X Syndrome: The Therapeutic Relevance of Cochlear Alterations and BKCa Channels
por: Ferraguto, Celeste, et al.
Publicado: (2023)

A synaptic F-actin network controls otoferlin-dependent exocytosis in auditory inner hair cells
por: Vincent, Philippe FY, et al.
Publicado: (2015)

The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses
por: Calvet, Charlotte, et al.
Publicado: (2022)

Synaptic vesicle release during ribbon synapse formation of cone photoreceptors
por: Davison, Adam, et al.
Publicado: (2022)

Developmental Acquisition of a Rapid Calcium-Regulated Vesicle Supply Allows Sustained High Rates of Exocytosis in Auditory Hair Cells
por: Levic, Snezana, et al.
Publicado: (2011)

Otoferlin acts as a Ca(2+) sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses
por: Michalski, Nicolas, et al.
Publicado: (2017)

Synaptic vesicles are “primed” for fast clathrin-mediated endocytosis at the ribbon synapse
por: Pelassa, Ilaria, et al.
Publicado: (2014)

Synaptic activity is not required for establishing heterogeneity of inner hair cell ribbon synapses
por: Karagulyan, Nare, et al.
Publicado: (2023)

Elementary properties of Ca(2+) channels and their influence on multivesicular release and phase-locking at auditory hair cell ribbon synapses
por: Magistretti, Jacopo, et al.
Publicado: (2015)

Cholinergic efferent synaptic transmission regulates the maturation of auditory hair cell ribbon synapses
por: Johnson, Stuart L., et al.
Publicado: (2013)

Autophagy-Mediated Synaptic Refinement and Auditory Neural Pruning Contribute to Ribbon Synaptic Maturity in the Developing Cochlea
por: Guo, Rui, et al.
Publicado: (2022)

Nanomachinery Organizing Release at Neuronal and Ribbon Synapses
por: Chakrabarti, Rituparna, et al.
Publicado: (2019)

Axonal Synapses Utilize Multiple Synaptic Ribbons in the Mammalian Retina
por: Kim, Hong-Lim, et al.
Publicado: (2012)

Role of intracellular calcium stores in hair-cell ribbon synapse
por: Castellano-Muñoz, Manuel, et al.
Publicado: (2014)

Macrophages Are Dispensable for Postnatal Pruning of the Cochlear Ribbon Synapses
por: Yu, Chaorong, et al.
Publicado: (2021)

Otoferlin as a multirole Ca(2+) signaling protein: from inner ear synapses to cancer pathways
por: Leclère, Jean-Christophe, et al.
Publicado: (2023)

Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma
por: Wan, Guoqiang, et al.
Publicado: (2014)

Functional maturation of the exocytotic machinery at gerbil hair cell ribbon synapses
por: Johnson, Stuart L, et al.
Publicado: (2009)

Lead exposure induces nitrative stress and disrupts ribbon synapses in the cochlea
por: Rosati, Rita, et al.
Publicado: (2022)

Postsynaptic Recordings at Afferent Dendrites Contacting Cochlear Inner Hair Cells: Monitoring Multivesicular Release at a Ribbon Synapse
por: Grant, Lisa, et al.
Publicado: (2011)

Functional and Structural Development of Mouse Cone Photoreceptor Ribbon Synapses
por: Davison, Adam, et al.
Publicado: (2022)

In vivo knockdown of Piccolino disrupts presynaptic ribbon morphology in mouse photoreceptor synapses
por: Regus-Leidig, Hanna, et al.
Publicado: (2014)

Presynaptic [Ca(2+)] and GCAPs: aspects on the structure and function of photoreceptor ribbon synapses
por: Schmitz, Frank
Publicado: (2014)

The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse
por: Becker, Lars, et al.
Publicado: (2018)

Cnr2 Is Important for Ribbon Synapse Maturation and Function in Hair Cells and Photoreceptors
por: Colón-Cruz, Luis, et al.
Publicado: (2021)

The Effects of Aging on Rod Bipolar Cell Ribbon Synapses
por: Shrestha, Abhishek P., et al.
Publicado: (2023)

Age-dependent structural reorganization of utricular ribbon synapses
por: Michanski, Susann, et al.
Publicado: (2023)

Endocytosis sustains release at photoreceptor ribbon synapses by restoring fusion competence
por: Wen, Xiangyi, et al.
Publicado: (2018)

APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses
por: Fanutza, Tomas, et al.
Publicado: (2015)

Disruption of Otoferlin Alters the Mode of Exocytosis at the Mouse Inner Hair Cell Ribbon Synapse
por: Takago, Hideki, et al.
Publicado: (2019)

Ciliary Proteins Repurposed by the Synaptic Ribbon: Trafficking Myristoylated Proteins at Rod Photoreceptor Synapses
por: Suiwal, Shweta, et al.
Publicado: (2022)

The mammalian rod synaptic ribbon is essential for Ca(v) channel facilitation and ultrafast synaptic vesicle fusion
por: Grabner, Chad Paul, et al.
Publicado: (2021)

ERG Responses in Mice with Deletion of the Synaptic Ribbon Component RIBEYE
por: Fairless, Richard, et al.
Publicado: (2020)

Ribbon Synapses and Retinal Disease: Review
por: Frederick, Courtney E., et al.
Publicado: (2023)

Calmodulin Bidirectionally Regulates Evoked and Spontaneous Neurotransmitter Release at Retinal Ribbon Synapses
por: Liang, Chao-Qun, et al.
Publicado: (2021)

Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse
por: Tagliatti, Erica, et al.
Publicado: (2016)

Rabconnectin-3α/DMXL2 Is Locally Enriched at the Synaptic Ribbon of Rod Photoreceptor Synapses
por: Dittrich, Alina, et al.
Publicado: (2023)

Synaptic Ribbon Active Zones in Cone Photoreceptors Operate Independently from One Another
por: Grassmeyer, Justin J., et al.
Publicado: (2017)

Tracking Newly Released Synaptic Vesicle Proteins at Ribbon Active Zones
por: Vaithianathan, Thirumalini, et al.
Publicado: (2019)

FGF22 deletion causes hidden hearing loss by affecting the function of inner hair cell ribbon synapses
por: Hou, Shule, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gjqpkbgaun64je81kufcmh3jp3