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DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation

The differentiation of oligodendrocyte precursor cells (OPCs) into myelinating oligodendrocytes is the prerequisite for remyelination in demyelinated disorders such as multiple sclerosis (MS). Epigenetic mechanisms, such as DNA methylation, have been suggested to control the intricate network of tra...

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Detalles Bibliográficos
Autores principales: Tiane, Assia, Schepers, Melissa, Riemens, Renzo, Rombaut, Ben, Vandormael, Patrick, Somers, Veerle, Prickaerts, Jos, Hellings, Niels, van den Hove, Daniel, Vanmierlo, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558293/
https://www.ncbi.nlm.nih.gov/pubmed/34482420
http://dx.doi.org/10.1007/s00018-021-03927-2