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DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation
The differentiation of oligodendrocyte precursor cells (OPCs) into myelinating oligodendrocytes is the prerequisite for remyelination in demyelinated disorders such as multiple sclerosis (MS). Epigenetic mechanisms, such as DNA methylation, have been suggested to control the intricate network of tra...
Autores principales: | Tiane, Assia, Schepers, Melissa, Riemens, Renzo, Rombaut, Ben, Vandormael, Patrick, Somers, Veerle, Prickaerts, Jos, Hellings, Niels, van den Hove, Daniel, Vanmierlo, Tim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558293/ https://www.ncbi.nlm.nih.gov/pubmed/34482420 http://dx.doi.org/10.1007/s00018-021-03927-2 |
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