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Targeted Inhibition of HK-II Reversed the Warburg Effect to Improve the Radiosensitivity of Laryngeal Carcinoma

PURPOSE: Hexokinase-II (HK-II) is the key enzyme in the first rate-limiting step of glycolysis that catalyzes the conversion of glucose to glucose-6-phosphate. Here, we examined the association between HK-II expression and radioresistance in laryngeal carcinoma and whether the inhibition of HK-II ex...

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Detalles Bibliográficos
Autores principales:	Chen, Xiao-Hong, Yu, Ding-Li, Zhong, Jiang-Tao, Zhou, Shui-Hong, Fan, Jun, Lu, Zhong-Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558321/ https://www.ncbi.nlm.nih.gov/pubmed/34737635 http://dx.doi.org/10.2147/CMAR.S324754

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