Pyruvate Kinase M2 Mediates Glycolysis Contributes to Psoriasis by Promoting Keratinocyte Proliferation

Psoriasis is characterized by keratinocyte proliferation and immune cell infiltration. M2 isoform of pyruvate kinase (PKM2) was reported to have an important role in cell proliferation, which is a rate-limiting enzyme that regulates the final step of glycolysis. However, how PKM2 regulates cell meta...

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Detalles Bibliográficos
Autores principales: Liu, Yun-zi, Xu, Ming-yuan, Dai, Xiao-yu, Yan, Lang, Li, Lei, Zhu, Rui-zhen, Ren, Li-jun, Zhang, Ji-qian-zhu, Zhang, Xiao-fang, Li, Jin-feng, Tian, Yi-jun, Shi, Wen-jing, Liu, Ye-qiang, Jiang, Chun-lei, Zhu, Jiang-bo, Chen, Ji-kuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558409/
https://www.ncbi.nlm.nih.gov/pubmed/34733164
http://dx.doi.org/10.3389/fphar.2021.765790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558409/
https://www.ncbi.nlm.nih.gov/pubmed/34733164
http://dx.doi.org/10.3389/fphar.2021.765790

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