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Pyruvate Kinase M2 Mediates Glycolysis Contributes to Psoriasis by Promoting Keratinocyte Proliferation
Psoriasis is characterized by keratinocyte proliferation and immune cell infiltration. M2 isoform of pyruvate kinase (PKM2) was reported to have an important role in cell proliferation, which is a rate-limiting enzyme that regulates the final step of glycolysis. However, how PKM2 regulates cell meta...
Autores principales: | Liu, Yun-zi, Xu, Ming-yuan, Dai, Xiao-yu, Yan, Lang, Li, Lei, Zhu, Rui-zhen, Ren, Li-jun, Zhang, Ji-qian-zhu, Zhang, Xiao-fang, Li, Jin-feng, Tian, Yi-jun, Shi, Wen-jing, Liu, Ye-qiang, Jiang, Chun-lei, Zhu, Jiang-bo, Chen, Ji-kuai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558409/ https://www.ncbi.nlm.nih.gov/pubmed/34733164 http://dx.doi.org/10.3389/fphar.2021.765790 |
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