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Nutraceutical Aid for Allergies – Strategies for Down-Regulating Mast Cell Degranulation

Interactions of antigens with the mast cell FcεRI-IgE receptor complex induce degranulation and boost synthesis of pro-inflammatory lipid mediators and cytokines. Activation of spleen tyrosine kinase (Syk) functions as a central hub in this signaling. The tyrosine phosphatase SHP-1 opposes Syk activ...

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Detalles Bibliográficos
Autores principales: McCarty, Mark F, Lerner, Aaron, DiNicolantonio, James J, Benzvi, Carina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558634/
https://www.ncbi.nlm.nih.gov/pubmed/34737578
http://dx.doi.org/10.2147/JAA.S332307

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