N6-methyladenosine regulates ATM expression and downstream signaling

N6-methyladenosine (m6A) is the most abundant modification in eukaryotic mRNAs, which plays an important role in regulating multiple biological processes. ATM is a major protein kinase that regulates the DNA damage response. Here, we identified that ATM is a m6A-modificated gene. METTL3 (a m6A “writ...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyue, Liu, Peishan, Zheng, Xiang, Wang, Jia, Peng, Qiu, Li, Zhengshuo, Wei, Lingyu, Liu, Can, Wu, Yangge, Wen, Yuqing, Yan, Qun, Ma, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558655/
https://www.ncbi.nlm.nih.gov/pubmed/34729106
http://dx.doi.org/10.7150/jca.64061

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