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Challenges in the Diagnosis of Intraocular Lymphoma
Intraocular lymphomas are among the rare malignancies that present with a wide variety of clinical manifestations. Differential diagnosis can be very troublesome due to its mimicking nature, insidious disease onset, and partial treatment response to steroids. The most important step in diagnosis is...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Galenos Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558694/ https://www.ncbi.nlm.nih.gov/pubmed/34702874 http://dx.doi.org/10.4274/tjo.galenos.2021.50607 |
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author | Kaya, Mahmut Öner, Ferit Hakan Lebe, Banu Özkal, Sermin Men, Süleyman Saatci, Ali Osman |
author_facet | Kaya, Mahmut Öner, Ferit Hakan Lebe, Banu Özkal, Sermin Men, Süleyman Saatci, Ali Osman |
author_sort | Kaya, Mahmut |
collection | PubMed |
description | Intraocular lymphomas are among the rare malignancies that present with a wide variety of clinical manifestations. Differential diagnosis can be very troublesome due to its mimicking nature, insidious disease onset, and partial treatment response to steroids. The most important step in diagnosis is a high index of suspicion. Signs of the disease are now easier to detect using multimodal imaging techniques. In this case series, we reviewed the clinical characteristics of two women aged 70 and 71 years and a 72-year-old man with intraocular lymphoma and described their multimodal imaging findings in detail. Bilateral eye involvement was present in all three cases at our first ophthalmological examination. While the disease first presented with ocular involvement in two of the three cases, ocular involvement was detected seven years after initial heart involvement in one patient. All three patients had diffuse large B-cell lymphomas (one diagnosed with retinal biopsy, one with conjunctival biopsy, and the remaining with stereotactic brain biopsy). Intraocular lymphoma should be diagnosed and treated using a multidisciplinary approach, and we share our experience in this case series. |
format | Online Article Text |
id | pubmed-8558694 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Galenos Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-85586942021-11-17 Challenges in the Diagnosis of Intraocular Lymphoma Kaya, Mahmut Öner, Ferit Hakan Lebe, Banu Özkal, Sermin Men, Süleyman Saatci, Ali Osman Turk J Ophthalmol Case Report Intraocular lymphomas are among the rare malignancies that present with a wide variety of clinical manifestations. Differential diagnosis can be very troublesome due to its mimicking nature, insidious disease onset, and partial treatment response to steroids. The most important step in diagnosis is a high index of suspicion. Signs of the disease are now easier to detect using multimodal imaging techniques. In this case series, we reviewed the clinical characteristics of two women aged 70 and 71 years and a 72-year-old man with intraocular lymphoma and described their multimodal imaging findings in detail. Bilateral eye involvement was present in all three cases at our first ophthalmological examination. While the disease first presented with ocular involvement in two of the three cases, ocular involvement was detected seven years after initial heart involvement in one patient. All three patients had diffuse large B-cell lymphomas (one diagnosed with retinal biopsy, one with conjunctival biopsy, and the remaining with stereotactic brain biopsy). Intraocular lymphoma should be diagnosed and treated using a multidisciplinary approach, and we share our experience in this case series. Galenos Publishing 2021-10 2021-10-26 /pmc/articles/PMC8558694/ /pubmed/34702874 http://dx.doi.org/10.4274/tjo.galenos.2021.50607 Text en © Copyright 2021 by Turkish Ophthalmological Association | Turkish Journal of Ophthalmology, published by Galenos Publishing House. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kaya, Mahmut Öner, Ferit Hakan Lebe, Banu Özkal, Sermin Men, Süleyman Saatci, Ali Osman Challenges in the Diagnosis of Intraocular Lymphoma |
title | Challenges in the Diagnosis of Intraocular Lymphoma |
title_full | Challenges in the Diagnosis of Intraocular Lymphoma |
title_fullStr | Challenges in the Diagnosis of Intraocular Lymphoma |
title_full_unstemmed | Challenges in the Diagnosis of Intraocular Lymphoma |
title_short | Challenges in the Diagnosis of Intraocular Lymphoma |
title_sort | challenges in the diagnosis of intraocular lymphoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558694/ https://www.ncbi.nlm.nih.gov/pubmed/34702874 http://dx.doi.org/10.4274/tjo.galenos.2021.50607 |
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