Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals

BACKGROUND: Precise gene dosage of the X chromosomes is critical for normal development and cellular function. In mice, XX female somatic cells show transcriptional X chromosome upregulation of their single active X chromosome, while the other X chromosome is inactive. Moreover, the inactive X chrom...

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Detalles Bibliográficos
Autores principales: Talon, Irene, Janiszewski, Adrian, Theeuwes, Bart, Lefevre, Thomas, Song, Juan, Bervoets, Greet, Vanheer, Lotte, De Geest, Natalie, Poovathingal, Suresh, Allsop, Ryan, Marine, Jean-Christophe, Rambow, Florian, Voet, Thierry, Pasque, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558763/
https://www.ncbi.nlm.nih.gov/pubmed/34724962
http://dx.doi.org/10.1186/s13059-021-02518-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558763/
https://www.ncbi.nlm.nih.gov/pubmed/34724962
http://dx.doi.org/10.1186/s13059-021-02518-5

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