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Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals

BACKGROUND: Precise gene dosage of the X chromosomes is critical for normal development and cellular function. In mice, XX female somatic cells show transcriptional X chromosome upregulation of their single active X chromosome, while the other X chromosome is inactive. Moreover, the inactive X chrom...

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Detalles Bibliográficos
Autores principales:	Talon, Irene, Janiszewski, Adrian, Theeuwes, Bart, Lefevre, Thomas, Song, Juan, Bervoets, Greet, Vanheer, Lotte, De Geest, Natalie, Poovathingal, Suresh, Allsop, Ryan, Marine, Jean-Christophe, Rambow, Florian, Voet, Thierry, Pasque, Vincent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558763/ https://www.ncbi.nlm.nih.gov/pubmed/34724962 http://dx.doi.org/10.1186/s13059-021-02518-5

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