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Chronic viral infections persistently alter marrow stroma and impair hematopoietic stem cell fitness

Chronic viral infections are associated with hematopoietic suppression, bone marrow (BM) failure, and hematopoietic stem cell (HSC) exhaustion. However, how persistent viral challenge and inflammatory responses target BM tissues and perturb hematopoietic competence remains poorly understood. Here, w...

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Detalles Bibliográficos
Autores principales:	Isringhausen, Stephan, Mun, YeVin, Kovtonyuk, Larisa, Kräutler, Nike J., Suessbier, Ute, Gomariz, Alvaro, Spaltro, Gianluca, Helbling, Patrick M., Wong, Hui Chyn, Nagasawa, Takashi, Manz, Markus G., Oxenius, Annette, Nombela-Arrieta, César
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558839/ https://www.ncbi.nlm.nih.gov/pubmed/34709350 http://dx.doi.org/10.1084/jem.20192070

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