Two distinct classes of thymic tumors in patients with MEN1 show LOH at the MEN1 locus

Patients with the multiple endocrine neoplasia type 1 (MEN1) syndrome carry germline heterozygous loss-of-function mutations in the MEN1 gene which predisposes them to develop various endocrine and non-endocrine tumors. Over 90% of the tumors show loss of heterozygosity (LOH) at chromosome 11q13, th...

Descripción completa

Detalles Bibliográficos
Autores principales: Mandl, Adel, Welch, James M, Kapoor, Gayathri, Parekh, Vaishali I, Schrump, David S, Ripley, R Taylor, Walter, Mary F, Del Rivero, Jaydira, Jha, Smita, Simonds, William F, Jensen, Robert T, Weinstein, Lee S, Blau, Jenny E, Agarwal, Sunita K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558845/
https://www.ncbi.nlm.nih.gov/pubmed/34515662
http://dx.doi.org/10.1530/ERC-21-0226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558845/
https://www.ncbi.nlm.nih.gov/pubmed/34515662
http://dx.doi.org/10.1530/ERC-21-0226

Ejemplares similares