Imaging of Dysfunctional Elastogenesis in Atherosclerosis Using an Improved Gadolinium-Based Tetrameric MRI Probe Targeted to Tropoelastin

[Image: see text] Dysfunctional elastin turnover plays a major role in the progression of atherosclerotic plaques. Failure of tropoelastin cross-linking into mature elastin leads to the accumulation of tropoelastin within the growing plaque, increasing its instability. Here we present Gd(4)-TESMA, a...

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Detalles Bibliográficos
Autores principales: Capuana, Federico, Phinikaridou, Alkystis, Stefania, Rachele, Padovan, Sergio, Lavin, Begoña, Lacerda, Sara, Almouazen, Eyad, Chevalier, Yves, Heinrich-Balard, Laurence, Botnar, René M., Aime, Silvio, Digilio, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558862/
https://www.ncbi.nlm.nih.gov/pubmed/34661390
http://dx.doi.org/10.1021/acs.jmedchem.1c01286

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