Clinical Impact of X-Ray Repair Cross-Complementary 1 (XRCC1) and the Immune Environment in Colorectal Adenoma–Carcinoma Pathway Progression

PURPOSE: Colorectal cancer (CRC) can develop via a hypermutagenic pathway characterized by frequent somatic DNA base-pair mutations. Alternatively, the immunogenicity of tumor cells themselves may influence the anticancer activity of the immune effector cells. Impaired DNA repair mechanisms drive mu...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Zhang, Xin, Jin, Zhuoyi, Chen, Huiyan, Zhang, Chenjing, Wang, wangyue, Jing, Jiyong, Pan, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559027/
https://www.ncbi.nlm.nih.gov/pubmed/34737598
http://dx.doi.org/10.2147/JIR.S331010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559027/
https://www.ncbi.nlm.nih.gov/pubmed/34737598
http://dx.doi.org/10.2147/JIR.S331010

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